Make the Diagnosis: Red Palms and Soles

(MedPage Today) -- Case Study: This 38 year-old female presents with an exanthem on her palms and soles associated with a sensation of skin tightness. No viral prodrome was noted. The patient has a neutral sexual history, is generally healthy, and takes no medications. She has no constitutional symptoms. Her past medical history is significant for a spontaneous DVT in her calf 2 years earlier. A biopsy of the lesion demonstrates microthrombi. What is your diagnosis?